Searchable abstracts of presentations at key conferences in endocrinology

ea0020p433 | Diabetes and Cardiovascular | ECE2009

The effect of telmisartan and irbesartan treatments on insulin resistance of patients with type 2 diabetes and hypertension

Tasli Babursah , Oz Gul Ozen , Tuncel Ercan , Guclu Metin , Kiyici Sinem , Imamoglu Sazi

Hyperinsulinemia that occurs due to insulin resistance play an important role on the development of type 2 diabetes and hypertension. It is shown that apart from their angiotensin II receptor blockage effect, telmisartan and irbesartan can activate intracellular hormone receptor PPARĪ³. Owing to this dual effect, telmisartan and irbesartan can improve cardiovascular risk factors related to insulin resistance. The aim of this study was to compare the effects of telmisartan ...